Research Overview

We conduct multidisciplinary research integrating advanced in vivo multi-organ imaging (e.g., brain and heart MRI), physiology and omics (e.g., metabolomics, proteomics), to understand the complex interrelationship between the brain and body systems across the lifespan, in health and neuropsychiatric diseases.

Main areas of research:

• Biophysiological axes (e.g., brain-immune, brain-eye, brain-heart) underlying the interplay between mental and physical comorbidities.
• Characteristics of intra- and inter-organ dynamics in aging.

We hope to leverage the above fundamental biological knowledge to:

• Develop evidence-based strategies to alleviate mental illness symptoms and physical comorbidity synergistically, and thus reducing physical health disparities in people with mental illness.
• Inform preventative strategies to extend healthy longevity and compress late-life morbidity.